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Pump-induced haemolysis: a comparison of short-term ventricular assist devices
M Bennett, S Horton, C Thuys, S Augustin, M Rosenberg, C Brizard
Royal Children’s Hospital, Parkville, Victoria, Australia
Perfusion 2004; 19: 107-111 |
Centrifugal pumps are superior to roller pumps for
extended support durations in terms of pump-induced
haemolysis. In this study, we evaluated the commonly
used Biomedicus BP 50 and compared it with the Jostra
Rotaflow and a standard roller pump in an in vitro test
circuit. Each circuit was run for a six-day period and
repeated five times. Plasma haemoglobin values showed
the roller pump to become more haemolytic than the
Biomedicus (p=0.022) and the Rotaflow. A statistically
significant difference between the Biomedicus and the
Rotaflow was observed on day six of the trial (p=0.016),
with the Rotaflow showing lower levels of haemolysis
than the Biomedicus. These results support the use of the
new generation centrifugal pump, the Rotaflow, as a
suitable device for short-term ventricular assist.
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